According to Michaël van de Poppe, the current altcoin market cycle presents a unique opportunity as he anticipates it may be the last 'easy' cycle before a major depression. Van de Poppe is prepared to endure a significant portfolio decline of 60-70% in pursuit of substantial gains, emphasizing the potential upside over imminent risks. This strategy suggests a high-risk, high-reward approach, relevant for traders assessing the volatility and timing in altcoin investments.